COLLAGE BIOSCIENCES

About the start-up

We are developing neurotherapeutics for neurodegeneration and the aging brain using programmable medicines that change the structure and function of disease associated proteins in the brain. By using advanced single cell RNA splicing methods to generate novel human data, we are identifying novel targets involved in neuroinflammation, neurometabolism, and neurotransmission.

Read more at collage-bio.com.

Project Title

CELLULAR TOOL DEVELOPMENT FOR GENETIC KIDNEY DISEASE THERAPIES

Project summary

The candidate will perform differentiations of stem cell-derived neural organoids and will apply single cell RNA splicing methods in various assay conditions. The candidate will perform oligonucleotide screens to identify lead drug candidates.

RESponsibility

• Stem cell culture and maintenance

• Molecular biology (PCR, western blot, qPCR)

• RNA splicing assays

• RNA sequencing

About the candidate

PLUSSES

Strong experience in molecular biology, cell culture (human stem cell culture preferred) and a background in RNA biology and neurobiology

• Ability to work closely in teams

• Attention to detail

• Enjoys a high-pressure environment

• Gets along with others

• Has a positive attitude

• Has a natural passion for science and discovery

• Motivated by the idea of developing new treatments for the brain