Montara Therapeutics

About the start-up

At Montara, they are developing safer, more efficacious therapies to improve the lives of patients with neurological diseases. Their mission is to develop innovative therapies for diseases of the brain by leveraging our proprietary platform to enhance drug safety and efficacy and enable the drugging of targets previously considered undruggable.

Introducing BrainOnly™, the uniquely versatile platform designed to prevent peripheral toxicities and concentrate neurological drugs’ activity in the brain, enhancing safety, increasing therapeutic index, and improving efficacy. Many promising drug candidates for neurological diseases fail to advance due to dose-limiting, off-tissue peripheral toxicities, which impede both safety and efficacy.

BrainOnly is a breakthrough platform that aims to prevent peripheral adverse events associated with neuroscience drugs. It holds the potential to deliver a new generation of brain-targeted therapeutics.

For more information, please visit montaratx.com.

Project Title

FUTURE OF MEDICINE

Project summary

As part of the team the Intern will play a pivotal role in our biomarker, discovery, and pharmacology efforts at Montara. This position offers an exciting opportunity to contribute to groundbreaking research and help shape the future of medicine. You will conduct cell-based assays, perform biochemical (cell-free) assays, and help with analyzing in vivo experiments.

RESponsibility

• Develop, optimize, and execute assays to test compounds for potency and target engagement in vitro assays.

• Develop, optimize, and execute assays to test for potency and target engagement in

• biofluids and tissues of animals dosed with our compounds.

• Work closely with the in vivo and chemistry teams in animal experiments and screening efforts.

• Stay up-to-date with new developments in the biomarker, cell-based assays, and screening field, and implement new technologies.

• Create clear and concise presentations summarizing the data generated.

• Write experimental reports in the electronic lab notebook.

About the candidate

Pluses

BS and MS (in progress) in a biology-related field, such as Cell Biology, Molecular Biology, Pharmacology, Biotechnology, etc.
Previous experience working in a laboratory is preferred.

Previous experience with culturing mammalian cells, ELISAs, Western Blotting, whole blood processing, tissue processing, FACS, imaging, etc