OneSkin Technologies - Extending the clinical application of senotherapeutic molecules

Short about the company

OneSkin is a longevity company committed to extending the healthy years of life and help people to age at their best. Our team of researchers and entrepreneurs is fascinated with science and living life to the fullest.

OneSkin is the first company growing human skin tissues in vitro that undergo the aging process. We have also identified biomarkers that can be accessed for measuring the success of a given intervention, and we have validated a new molecule, selected by our screening platform confirming their ability to reverse/prevent aging. This molecule reduces 25-50% of the aged cells (senescent cells) in the testing models. Our solution was designed to perform the whole discovery and validation processes of novel age reversal molecules and accelerate their translation to the clinic. Our new molecule is expected to be the first product in the skincare market with a senotherapeutical approach and holds greater and more impactful applications on skin aging.

Position/Project summary

OneSkin is looking for a Bioengineer focused student to join our R&D team. We are exploring new therapeutic applications to our lead molecule. We are looking for an intern to help on the optimization and validation of a 3D wound healing model and/or other skin disease model (eczema and psoriasis).

Job responsibilities

Main responsibilities will include (but are not limited to):

The research scientist will be responsible for cell culture and growing 3D wound healing models. The candidate will perform in vitro assays to evaluate cell migration after exposing the wounds to different compounds. Optimization on the wound size and time-point of analysis will be done. Next, the intern will test the potential of different compounds to promote wound healing, by measuring cell migration, morphology changes and gene expression.

The inter will also help with lab organization and documentation.

During the period of the internship, OneSkin will be launching their first product on the market, a skincare product delivered directly to consumer. The intern will be able to experience this process and help with any assigned task.

The findings from this project will help guide OneSkin next therapeutic application for their proprietary compounds.

Required skills/ Qualifications

It is expected to the intern function well within a team setting, be able to complete tasks on time and communicate well with company management.

Laboratory Skills:

Mammalian cell culture, 3D tissue culture (ideally but not required), RNA isolation, qPCR, DNA isolation, microscope imaging, and bioinformatics experience (preferred but not required).

Preferred qualifications:

The ideal candidate will have a B.A in bioengineering, cellular biology, or similar program.